.jpg "Eunsol Yang, PharmD, PhD photo")
Postdoctoral Scholar
University of California, San Francisco
I am Eunsol Yang, PharmD, PhD, currently working as a postdoctoral scholar in the field of Pharmacometrics in Dr. Rada Savic's lab at the University of California, San Francisco. My research focuses on the application of mechanistic pharmacokinetic (PK)-pharmacodynamic (PD) model-based approaches to translate preclinical findings into clinical outcomes and evaluate influential factors on drug response and disease dynamics, optimizing therapies.
My academic and research training have provided me an outstanding background in pharmaceutical sciences, clinical pharmacology, and pharmacometrics. During my PhD, I participated as the main investigator in over 10 early-phase clinical trials, including first-in-human studies and drug interaction studies, and identified clinical pharmacology properties of multiple novel drugs across various therapeutic areas. Leveraging data obtained from these clinical trials, I applied mechanistic and population PK modeling to optimize dosing regimens and trial designs, addressing knowledge gaps in drug development and clinical application. This all provided me comprehensive knowledge, proficient skills, and practical experience in clinical pharmacology research and pharmacometric modeling&simulation. My current work involves mechanism-based translational and population PK/PD modeling of drugs in the fields of type 2 diabetes, oncology, and tuberculosis. I believe this work can bridge knowledge gaps in drug development and clinical application, ultimately contributing to global health.